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For Immediate Release November 11, 2002
AuRx, Inc. - Baltimore
Dr. Joseph Burnett,will discuss the recently completed one year
follow-up data for the Phase I/II clinical trial of the AuRx therapeutic
vaccine for prevention of genital herpes at the Eugene Bereston
Lecture on Nov 19, 2002.
The results of the low dose arm of the trial were recently published
in Cutis, a dermatological journal. In that study, the publication
reported the recurrence rate was reduced 84% from the previous year
(P<.001) and 37.5% of the treated patients had no recurrent episodes
(complete prevention of all symptoms) (P=.06). The study achieved
statistical significance in all the secondary endpoints, including
reduction of illness days and reduction of recurrences.
The severity (pain, itching, lesions, vesicle formation, dysuria)
and duration of attacks in those patients having episodes was considerably
reduced. Further patient follow-up and scientific studies of the
patients in this trial are being envisaged to examine its disease-modifying
effects over the long-term. Additional new studies are being planned
to confirm these promising findings.
In the high dose arm, two shots of 10^6 pfu were given as opposed
to three shots of 105 pfu which were given in the low dose arm.
Genital herpes affects over 60 million Americans with 910,000 women
and 730,000 men contracting the disease each year. This disease
normally results in 6 outbreaks per year but in severe cases more
episodes may result. Increasing resistance to the nucleoside analogs
currently used to treat genital herpes is being reported. The psychosocial
consequences of genital herpes is quite significant as 57% of those
infected indicate that herpes interfered with their sexual relationships,
50% felt it was difficult to live with genital herpes and 37% felt
that herpes ruined their lives.
The Eugene Sydney Bereston Memorial Lecture is given annually by
an invitee of the Maryland Dermatologic Society and is dedicated
to an outstanding scientist and physician who studied cutaneous
diseases for many years. The lecture by Dr. Burnett will be given
on November 19, 2002 at the University of Maryland School of Social
Work auditorium at 525 West Redwood Street at 1:15 PM.
or Additional Information Contact:
Gary J. Calton, President AuRx, Inc.
500 J McCormick Drive
Glen Burnie, MD 21061
410.590.7610
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